Normal Tissues

Comparison mode

KDM6A

Brain

Cerebrum, grey matter

Cerebrum, white matter

Cerebellum, cortex (molecular layer, Purkinje cell layer, granule layer)

Cerebellum (white matter)

Endocrine Tissues

Adrenal gland

Adrenal gland – Moderate to strong nuclear KDM6A staining of adrenocortical cells

Thyroid gland

Thyroid gland – Moderate to strong nuclear KDM6A staining of follicular epithelial cells

Parathyroid gland

Parathyroid gland – Moderate to strong nuclear KDM6A staining of epithelial cells

Pituitary gland, anterior lobe

Pituitary gland, anterior lobe – Moderate to strong nuclear KDM6A staining of epithelial cells

Pituitary gland, posterior lobe

Pituitary gland, posterior lobe – Faint nuclear KDM6A staining of pituicytes

Respiratory system

Lung

Lung – Moderate to strong nuclear KDM6A staining of all cell types

Bronchus, glands

Bronchus, glands – Moderate to strong nuclear KDM6A staining of respiratory epithelial cells

Proximal digestive tract

Tonsil, surface epithelium

Tonsil, surface epithelium – Strong nuclear KDM6A staining of squamous epithelial cells and of lymphocytes

Parotid gland

Parotid gland – Moderate to strong nuclear KDM6A staining of all epithelial cells

Gastronintestinal tract

Stomach, antrum

Stomach, antrum – Moderate to strong nuclear KDM6A staining of epithelial cells. The staining is weaker in glandular cells than in superficial epithelium

Stomach, corpus

Stomach, corpus – Moderate to strong nuclear KDM6A staining of epithelial cells. The staining is weaker in glandular cells than in superficial epithelium

Duodenum, Brunner gland

Duodenum, Brunner gland – Moderate to strong nuclear KDM6A staining of Brunner gland cells

Colon descendens, mucosa

Colon descendens, mucosa – Moderate to strong nuclear KDM6A staining of epithelial cells. Staining is more intense in the crypt base than in the superficial epithelial cell layers

Liver, Gallbladder, Pancreas

Liver

Liver – Moderate nuclear KDM6A staining of hepatocytes. Stronger staining of other cell types_

Pancreas

Pancreas – Moderate to strong nuclear KDM6A staining of acinar cells. Stronger staining of ductal and islet cells

Kidney, urinary bladder

Kidney, cortex

Kidney, cortex – Moderate nuclear KDM6A staining of epithelial cells of all types

Kidney, medulla

Kidney, medulla – Moderate nuclear KDM6A staining of collecting ducts cells

Urinary bladder, urothelium

Urinary bladder, urothelium – Strong nuclear KDM6A staining of urothelial cells

Male tissues

Prostate

Prostate – Moderate nuclear KDM6A staining of all epithelial cells

Seminal vesicle

Seminal vesicle – Strong nuclear KDM6A staining of epithelial cells

Epididymis

Epididymis – Moderate nuclear KDM6A staining of epithelial cells of the cauda. Staining is less intense in basal cells

Testis

Testis – Moderate to strong nuclear KDM6A staining of Sertoli cells. KDM6A staining is weak in spermatogonia and virtually absent in more mature cells of spermatogenesis

Female Tissues

Breast

Breast – Strong nuclear KDM6A staining of basal and luminal cells

Uterus, ectocervix

Uterus, ectocervix – Moderate to strong nuclear KDM6A staining of squamous epithelial cells

Uterus, endocervix

Uterus, endocervix – Strong nuclear KDM6A staining of epithelial cells

Uterus, endometrium (proliferation)

Uterus, endometrium (proliferation) – Strong nuclear KDM6A staining of epithelial and stromal cells

Uterus, endometrium (pregnancy)

Uterus, endometrium (pregnancy) – Moderate to strong nuclear KDM6A staining of all cells

Uterus, endometrium (secretion)

Uterus, endometrium (secretion) – Strong nuclear KDM6A staining most glandular cells.jpeg

Uterus, myometrium

Uterus, myometrium – Moderate to strong nuclear KDM6A staining of muscular cells

Fallopian tube, mucosa

Fallopian tube, mucosa – Strong nuclear KDM6A staining of all epithelial cells

Ovary, stroma

Ovary, stroma – Moderate nuclear KDM6A staining of stroma cells

Ovary, corpus luteum

Ovary, corpus luteum – Strong nuclear KDM6A staining of corpus luteum cells

Placenta (amnion and chorion)

Placenta (amnion and chorion) – Weak to moderate nuclear KDM6A staining of amnion cells. Moderate to strong staining of chorion cells

Placenty, early

Placenty, early – Strong nuclear KDM6A staining of trophoblastic cells, stroma cells and endothelial cells

Placenta, mature

Placenta, mature – Strong nuclear KDM6A staining of trophoblastic cells, stroma cells and endothelial cells

Muscle, connective & soft tissue

Skeletal muscle

Skeletal muscle – Moderate nuclear KDM6A staining of muscular cells

Aorta, media

Aorta, media – Weak nuclear KDM6A staining of cells

Heart muscle

Heart muscle – Weak to moderate nuclear KDM6A staining of heart muscle cells

Urinary bladder, muscular wall

Urinary bladder, muscular wall – Weak to moderate nuclear KDM6A staining of muscular cells

Appendix, muscular wall

Appendix, muscular wall – Weak to moderate nuclear KDM6A staining of muscular and ganglion cells

Colon descendens, muscular wall

Colon descendens, muscular wall – Weak to moderate nuclear KDM6A staining of muscular cells

Skin

Skin – Moderate to strong nuclear KDM6A staining of squamous epithelial cells

Bone Marrow & lymphoid tissues

Bone marrow

Bone marrow – Strong nuclear KDM6A staining of virtually all cells

Thymus

Thymus – Intense nuclear KDM6A staining of all cell types

Spleen

Spleen – Moderate to strong staining of all cell types

Spleen

Lymph node

Lymph node – Moderate to strong staining of lymphocytes and other cell types

Tonsil

Tonsil – Intense nuclear KDM6A staining of all cell types