Cancer Tissues

KDM6A

Endocrine Tissues

Adrenal gland

Adrenal gland – Adrenocortical adenoma with moderate KDM6A staining of tumor cells

Thyroid

Thyroid – Anaplastic carcinoma with complete absence of KDM6 staining in tumor cells

Thyroid

Thyroid – Papillary cancer with strong KDM6A staining of tumor cells

Respiratory system

Lung

Lung – Adenocarcinoma with strong KDM6A staining of tumor cells

Lung

Lung – Squamous cell carcinoma with strong KDM6A positivity of tumor cells

Proximal digestive tract

Esophagus

Esophagus – Adenocarcinoma with strong KDM6A staining of tumor cells

Esophagus

Esophagus – Squamous cell carcinoma showing a strong KDM6A positivity of tumor cells

Salivary gland

Salivary gland – Warthin tumor with moderate to strong KDM6A staining of tumor cells

Gastronintestinal tract

Stomach

Stomach – Gastric adenocarcinoma (intestinal type) with moderate KDM6A staining of tumor cells

Stomach

Stomach – Gastrointestinal stromal tumor (GIST) showing a strong KDM6A staining of all tumor cells

Colon

Colon – Colorectal adenocarcinoma with strong KDM6A staining of tumor cells

Liver, Gallbladder, Pancreas

Pancreas

Pancreas – Ductal adenocarcinoma with complete absence of KDM6 staining in tumor cells

Pancreas

Pancreas – Neuroendocrine tumor with strong KDM6A positivity of tumor cells

Kidney, urinary bladder

Kidney

Kidney – Clear cell renal cell carcinoma with weak KDM6A staining of tumor cells

Kidney

Kidney – Papillary renal cell carcinoma with strong KDM6A positivity of tumor cells

Urinary bladder

Urinary bladder – Muscle-invasive urothelial carcinoma with complete absence of KDM6 staining in tumor cells

Urinary bladder

Urinary bladder – Muscle-invasive urothelial carcinoma with complete absence of KDM6A staining in tumor cells. (2)

Urinary bladder

Urinary bladder – Muscle-invasive urothelial carcinoma with complete absence of KDM6A staining in tumor cells

Urinary bladder

Urinary bladder – Muscle-invasive urothelial carcinoma with strong KDM6A staining of tumor cells

Urinary bladder

Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) with complete lack of KDM6 staining in tumor cells

Kidney, pelvis

Kidney, pelvis – Invasive urothelial carcinoma lacking KDM6 staining in tumor cells

Male tissues

Prostate

Prostate – Adenocarcinoma (Gleason 3+3=6) with moderate intensity KDM6A staining of tumor cells

Testis

Testis – Leydig cell tumor with weak to moderate KDM6A staining of tumor cells

Testis

Testis – Seminoma with strong KDM6A immunostaining of tumor cells

Female Tissues

Breast

Breast – Invasive breast cancer of no special type (NST) with strong KDM6A staining of all tumor cells

Breast

Breast – Invasive lobular breast cancer with strong KDM6A positivity of tumor cells

Ovary

Ovary – Clear cell carcinoma with strong KDM6A positivity of tumor cells

Ovary

Ovary – Serous high-grade carcinoma with complete absence of KDM6 staining in tumor cells

Ovary

Ovary – Serous high-grade carcinoma with strong KDM6A immunostaining of tumor cells

Muscle, connective & soft tissue

Penis

Penis – Squamous cell carcinoma with strong KDM6A staining of tumor cells

Skin

Skin – Malignant melanoma with strong nuclear KDM6A positivity of tumor cells

Skin

Skin – Squamous cell carcinoma with moderate intensity KDM6A staining of tumor cells

Bone Marrow & lymphoid tissues

Lymph node

Lymph node – Diffuse large B-cell lymphoma with complete absence of KDM6 staining in tumor cells

Lymph node

Lymph node – Diffuse large B-cell lymphoma with strong KDM6A immunostaining of tumor cells

Lymph node

Lymph node – Follicular B-cell lymphoma with lack of KDM6 staining in tumor cells

Lymph node

Lymph node – Hodgkin’s lymphoma with strong KDM6A staining of tumor cells and of tumor adjacent normal lymphatic tissue