Cancer Tissues

Endocrine Tissues

Adrenal gland
Adrenal gland – NFIX negative adrenocortical adenoma
Adrenal gland
Adrenal gland – NFIX negative pheochromocytoma

Respiratory system

Lung
Lung – Adenocarcinoma with strong NFIX staining of tumor cells

Proximal digestive tract

Esophagus
Esophagus – Adenocarcinoma with a moderate nuclear NFIX staining ofa subset of tumor cells
Esophagus
Esophagus – Squamous cell carcinoma with strong nuclear NFIX staining of tumor cells
Salivary gland
Salivary gland – Warthin tumor with strong NFIX positivity of epithelial tumor cells

Gastronintestinal tract

Stomach
Stomach – Gastric adenocarcinoma (intestinal type) with moderate NFIX immunostaining of tumor cells
Stomach
Stomach – Gastrointestinal stromal tumor (GIST) with strong nuclearNFIX positivity of tumor cells
Stomach
Stomach – NFIX negative gastric adenocarcinoma (diffuse type)
Colon
Colon – Colorectal adenocarcinoma with moderate nuclear NFIX staining of most tumor cells.jpeg
Colon
Colon – Colorectal adenocarcinoma with strong NFIX staining of tumor cells

Liver, Gallbladder, Pancreas

Liver
Liver – Cholangiocellular carcinoma with strong nuclear NFIX staining of tumor cells
Liver
Liver – Hepatocellular carcinoma with strong NFIX staining of tumor cells.jpeg
Pancreas
Pancreas – Ductal adenocarcinoma showing a weak NFIX staining of a subset of tumor cells
Pancreas
Pancreas – NFIX negative neuroendocrine tumor

Kidney, urinary bladder

Kidney
Kidney – NFIX negative clear cell carcinoma.jpeg
Kidney
Kidney – Papillary renal cell carcinoma with moderate nuclear NFIX staining of tumor cells
Urinary bladder
Urinary bladder – Muscle-invasive urothelial carcinoma with strong NFIX staining of all tumor cells
Urinary bladder
Urinary bladder – Non-invasive papillary urothelial carcinoma (pTa) with only a faint NFIX staining of few cells.jpeg

Male tissues

Prostate
Prostate – Adenocarcinoma (Gleason 3+3=6) with strong NFIX staining of tumor cells
Testis
Testis – Leydig cell tumor with strong nuclear NFIX staining of all tumor cells
Testis
Testis – NFIX negative seminoma

Female Tissues

Breast
Breast – Invasive breast cancer of no special type (NST) with moderatenuclear NFIX staining of only few tumor cells
Breast
Breast – Invasive lobular breast cancer with strong nuclear NFIX staining of all tumor cells
Uterus, cervix
Uterus, cervix – Squamous cell carcinoma with strong NFIX immunostaining of tumor cells
Uterus
Uterus – Leiomyoma with strong NFIX positivity of tumor cells
Ovary
Ovary – Malignant mixed Mullerian tumor with strong nuclear NFIX staining of mesenchymal tumor cells while staining is only faint in epithelial tumor cells
Ovary
Ovary – NFIX negative clear cell carcinoma
Ovary
Ovary – Serous high-grade carcinoma with strong nuclear NFIX staining of all tumor cells

Skin

Skin
Skin – Basal cell carcinoma with strong NFIX immunostaining of tumor cells
Skin
Skin – Squamous cell carcinoma with strong NFIX immunostaining of tumor cells
Anal canal
Anal canal – Squamous cell carcinoma with strong nuclear NFIX staining of tumor cells

Bone Marrow & lymphoid tissues

Lymph node
Lymph node – NFIX negative diffuse large B-cell lymphoma. Strong NFIX staining of few interspersed non-neoplastic cells
Lymph node
Lymph node – NFIX negative follicular B-cell lymphoma. Strong NFIX staining of few interspersed non-neoplastic cells