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Normal Tissues
Comparison mode
KAP1 / TRIM28
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Cancer Tissues
Brain
Cerebrum, grey matter (2)
Cerebrum, grey matter
Cerebrum, white matter
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum (white matter)
Endocrine Tissues
Adrenal gland
Parathyroid gland
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe
Respiratory system
Lung
Proximal digestive tract
Rectum, mucosa
Rectum, mucosa – The intensity of nuclear TRIM28 staining decreases slightly from the crypt base to the surface epithelium
Tonsil, surface epithelium
Tonsil, surface epithelium – The intensity of nuclear TRIM28 staining decreases slightly from the basal to the top cell layers
Parotid gland
Gastronintestinal tract
Stomach, antrum
Duodenum, Brunner gland
Liver, Gallbladder, Pancreas
Liver
Liver – Nuclear TRIM28 staining is absent in hepatocytes but strong in other cell types of this sample
Liver
Liver – Nuclear TRIM28 staining is largely absent in hepatocytes of this sample
Pancreas
Kidney, urinary bladder
Kidney, cortex
Kidney, medulla
Urinary bladder, urothelium
Male tissues
Epididymis (Cauda)
Epididymis (Corpus)
Prostate
Seminal vesicle
Testis
Testis – Strong nuclear TRIM28 staining in all cells. Exception- Spermatids are TRIM28 negative
Female Tissues
Breast
Uterus, ectocervix
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion) (2)
Uterus, endometrium (secretion)
Uterus, myometrium
Uterus, myometrium – Strong nuclear TRIM28 staining of all cells
Fallopian tube, mucosa
Ovary, stroma
Ovary, stroma – Strong nuclear TRIM28 staining of all cells
Ovary, corpus luteum
Placenta (amnion and chorion)
Placenta, early
Placenta, mature
Muscle, connective & soft tissue
Skeletal muscle
Aorta, media
Heart muscle
Heart muscle – Strong nuclear TRIM28 staining of all cells
Urinary bladder, muscular wall
Colon descendens, mucosa
Colon descendens, mucosa – The intensity of nuclear TRIM28 staining decreases slightly from the crypt base to the surface epithelium
Colon descendens, mucosa
Colon descendens, muscular wall
Skin
Skin
Skin, hairfollicel and sebaceous glands
Anal canal, skin
Anal canal, skin – The intensity of nuclear TRIM28 staining decreases slightly from the basal to the top cell layers
Bone Marrow & lymphoid tissues
Bone marrow
Thymus
Spleen
Tonsil (2)
Tonsil