Stomach, antrum – Strong nuclear MRE11 staining of all cells. A distinct cytoplasmic MRE11 staining of parietal cells represents a (tolerable) cross-reactivity
Stomach, antrum
Duodenum, Brunner gland
Liver, Gallbladder, Pancreas
Liver
Liver – Strong nuclear MRE11 staining of most cell types. In this sample, MRE11 staining is completely absent in hepatocytes
Liver
Liver – Strong nuclear MRE11 staining of most cells. In this sample, MRE11 staining is absent in hepatocytes
Liver
Liver – Strong nuclear MRE11 staining of most cells. MRE11 staining is weaker (weak to moderate) in hepatocytes
Pancreas
Kidney, urinary bladder
Kidney, cortex
Kidney, medulla
Kidney, pelvis, urothelium
Kidney, pelvis, urothelium – Strong nuclear MRE11 staining of all cells. In addition, a weak to moderate cytoplasmic MRE11 staining occurs in some samples
Urinary bladder, urothelium
Urinary bladder, urothelium – Strong nuclear MRE11 staining of all cells
Male tissues
Epididymis (Cauda)
Epididymis (Corpus)
Prostate
Seminal vesicle
Testis
Testis – Distinct nuclear MRE11 staining of all cells although the staining intensity of germ cells decreases from spermatogonia to spermatids
Female Tissues
Breast
Uterus, ectocervix
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion)
Fallopian tube, mucosa
Ovary, stroma
Ovary, corpus luteum
Placenta (amnion and chorion)
Placenta, early
Placenta, early – Distinct nuclear MRE11 staining of all cells. In addition, weak to moderate cytoplasmic staining of trophoblast cells
Placenta, mature
Placenta, mature – Distinct nuclear MRE11 staining of all cells, although the nuclear staining is somewhat weaker in syncytiotrophoblast cells than in all other cell types
Muscle, connective & soft tissue
Skeletal muscle
Skeletal muscle – Strong nuclear MRE11 staining of all cells
Aorta, media
Heart muscle
Heart muscle – Strong nuclear MRE11 staining of all cells
Urinary bladder, muscular wall
Appendix, muscular wall
Appendix, muscular wall – Strong nuclear MRE11 staining of all cells
Colon descendens, mucosa
Colon descendens, mucosa – Distinct nuclear MRE11 staining of all cells. Slight but significant decrease of MRE11 staining from the crypt baseto the superficial epithelial cell layers
Colon descendens, muscular wall
Skin
Skin
Skin, hairfollicel and sebaceous glands
Bone Marrow & lymphoid tissues
Bone marrow
Thymus
Thymus – Strong nuclear MRE11 staining of all cells. A few dispersed cells stand out because of a particularly strong nuclear MRE11 staining