Normal Tissues

Brain

Cerebrum, grey matter
Cerebrum, white matter
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum (white matter)

Endocrine Tissues

Adrenal gland
Thyroid gland
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe

Respiratory system

Lung

Proximal digestive tract

Tonsil, surface epithelium
Parotid gland

Gastronintestinal tract

Stomach, antrum
Stomach, antrum – Strong nuclear MRE11 staining of all cells. A distinct cytoplasmic MRE11 staining of parietal cells represents a (tolerable) cross-reactivity
Stomach, antrum
Duodenum, Brunner gland

Liver, Gallbladder, Pancreas

Liver
Liver – Strong nuclear MRE11 staining of most cell types. In this sample, MRE11 staining is completely absent in hepatocytes
Liver
Liver – Strong nuclear MRE11 staining of most cells. In this sample, MRE11 staining is absent in hepatocytes
Liver
Liver – Strong nuclear MRE11 staining of most cells. MRE11 staining is weaker (weak to moderate) in hepatocytes
Pancreas

Kidney, urinary bladder

Kidney, cortex
Kidney, medulla
Kidney, pelvis, urothelium
Kidney, pelvis, urothelium – Strong nuclear MRE11 staining of all cells. In addition, a weak to moderate cytoplasmic MRE11 staining occurs in some samples
Urinary bladder, urothelium
Urinary bladder, urothelium – Strong nuclear MRE11 staining of all cells

Male tissues

Epididymis (Cauda)
Epididymis (Corpus)
Prostate
Seminal vesicle
Testis
Testis – Distinct nuclear MRE11 staining of all cells although the staining intensity of germ cells decreases from spermatogonia to spermatids

Female Tissues

Breast
Uterus, ectocervix
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion)
Fallopian tube, mucosa
Ovary, stroma
Ovary, corpus luteum
Placenta (amnion and chorion)
Placenta, early
Placenta, early – Distinct nuclear MRE11 staining of all cells. In addition, weak to moderate cytoplasmic staining of trophoblast cells
Placenta, mature
Placenta, mature – Distinct nuclear MRE11 staining of all cells, although the nuclear staining is somewhat weaker in syncytiotrophoblast cells than in all other cell types

Muscle, connective & soft tissue

Skeletal muscle
Skeletal muscle – Strong nuclear MRE11 staining of all cells
Aorta, media
Heart muscle
Heart muscle – Strong nuclear MRE11 staining of all cells
Urinary bladder, muscular wall
Appendix, muscular wall
Appendix, muscular wall – Strong nuclear MRE11 staining of all cells
Colon descendens, mucosa
Colon descendens, mucosa – Distinct nuclear MRE11 staining of all cells. Slight but significant decrease of MRE11 staining from the crypt baseto the superficial epithelial cell layers
Colon descendens, muscular wall

Skin

Skin
Skin, hairfollicel and sebaceous glands

Bone Marrow & lymphoid tissues

Bone marrow
Thymus
Thymus – Strong nuclear MRE11 staining of all cells. A few dispersed cells stand out because of a particularly strong nuclear MRE11 staining
Lymph node