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Normal Tissues
Comparison mode
TYMS
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Cancer Tissues
Brain
Cerebrum, grey matter
Cerebrum, white matter
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum (white matter)
Endocrine Tissues
Adrenal gland
Thyroid gland
Parathyroid gland
Parathyroid gland
Pituitary gland, posterior lobe (2)
Pituitary gland, posterior lobe
Respiratory system
Lung
Bronchus, glands
Proximal digestive tract
Tonsil, surface epithelium
Tonsil, surface epithelium – Weak to moderate, predominantly nuclear TYMS staining of a subset of suprabasal squamous epithelial cells
Gastronintestinal tract
Stomach, antrum
Stomach, antrum – Weak to moderate, nuclear and cytoplasmic TYMS staining of a fraction of epithelial cells
Stomach, corpus
Stomach, corpus – Weak to moderate, nuclear and cytoplasmic TYMS staining of a fraction of epithelial cells
Duodenum, Brunner gland
Colon descendens, mucosa
Colon descendens, mucosa – Faint, nuclear and cytoplasmic TYMS staining of a fraction of crypt epithelial cells
Liver, Gallbladder, Pancreas
Liver
Pancreas
Pancreas – Weak to moderate, nuclear and cytoplasmic TYMS staining of very few epithelial cells
Kidney, urinary bladder
Kidney, cortex
Kidney, medulla
Urinary bladder, urothelium
Male tissues
Prostate
Seminal vesicle
Testis
Testis – Weak to moderate, nuclear and cytoplasmic TYMS staining of spermatocytes
Female Tissues
Breast
Breast – Strong, nuclear and cytoplasmic TYMS staining of a subset of luminal epithelial cells of breast glands
Uterus, ectocervix
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion)
Uterus, myometrium
Fallopian tube, mucosa
Ovary, stroma
Ovary, corpus luteum
Ovary, corpus luteum – Moderate to strong, nuclear and cytoplasmic TYMS staining of some endothelial cells
Placenta (amnion and chorion) (2)
Placenta (amnion and chorion)
Placenta (amnion and chorion)
Placenta, early
Placenta, early – Variable, weak to strong, nuclear and cytoplasmic TYMS staining of few cells (cytotrophoblast, stromal)
Placenta, mature
Placenta, mature – TYMS staining is lacking in this sample
Placenta, mature
Placenta, mature – Variable, weak to strong, nuclear and cytoplasmic TYMS staining of few cells (trophoblast, endothelial)
Muscle, connective & soft tissue
Skeletal muscle
Aorta, media
Heart muscle
Urinary bladder, muscular wall
Appendix, muscular wall
Colon descendens, muscular wall
Skin
Skin
Bone Marrow & lymphoid tissues
Bone marrow
Bone marrow – Moderate to strong, nuclear and cytoplasmic TYMS staining of a large subset of hematopoetic cells
Thymus
Thymus – Strong TYMS staining of a large fraction of lymphocytes
Spleen
Spleen – Moderate to strong TYMS staining of a fraction of lymphocytic cells
Lymph node
Lymph node – Strong TYMS staining of a fraction of lymphocytic cells
Tonsil
Tonsil – Variable, moderate to strong, nuclear and cytoplasmic TYMS staining of a fraction of lymphocytes, especially in a germinal centre. (2)
Tonsil
Tonsil – Variable, moderate to strong, nuclear and cytoplasmic TYMS staining of a fraction of lymphocytes, especially in a germinal centre