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Normal Tissues

GPX2

Brain

Cerebrum, grey matter
Cerebrum, white matter
Cerebellum, cortex (grey)
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Endocrine Tissues

Adrenal gland
Thyroid gland
Parathyroid gland
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe

Respiratory system

Lung
Bronchus, glands
Bronchus, glands – In some cases, all cells of the respiratory epithelium show intense nuclear and cytoplasmic GPX2 staining

Proximal digestive tract

Tonsil, surface epithelium
Sublingual gland
Sublingual gland – Intense, predominantly cytoplasmic GPX2 staining of of some excretory duct cells
Parotid gland
Parotid gland – Intense, predominantly cytoplasmic GPX2 staining of most cells of some (but not all) excretory ducts

Gastronintestinal tract

Stomach, antrum
Stomach, antrum – Strong GPX2 staining of the surface epithelium with strongest staining in the most superficial cells. Parietal cells do also show significant staining
Stomach, antrum
Stomach, antrum - GPX2 staining is strong in the surface epithelium and strongest in the most apical (luminal) epithelial cells. Staining is only minimal in gastric glands (exception: parietal cells).
Stomach, corpus
Stomach, corpus –Strong GPX2 nuclear and cytoplasmic staining of the surface epithelium with strongest staining seen in in the most superficial cells. Only weak GPX2 staining of gastric glands
Duodenum, Brunner gland
Duodenum, Brunner gland – Brunner gland cells are GPX2 negative
Colon descendens, mucosa
Colon descendens, mucosa – Strong predominantly cytoplasmic GPX2 staining of epithelial cells - predominantly in the crypts. A luminal membrane staining can also be seen

Liver, Gallbladder, Pancreas

Liver
Liver – Strong predominantly cytoplasmic GPX2 staining of bile duct cells. Weak to moderate nuclear and cytoplasmic staining of liver cells
Pancreas
Pancreas – Significant, predominantly cytoplasmic GPX2 staining of excretory duct cells
Pancreas
Pancreas – Weak, predominantly nuclear GPX2 staining of pancreatic islet cells

Kidney, urinary bladder

Kidney, cortex
Kidney, medulla
Kidney, pelvis, urothelium
Kidney, pelvis, urothelium – Intense nuclear and cytoplasmic GPX2 staining of urothelial cells (except umbrella cells)
Urinary bladder, urothelium
Urinary bladder, urothelium – Intense nuclear and cytoplasmic GPX2 staining of urothelial cells

Male tissues

Prostate
Prostate – Weak to moderate, nuclear and cytoplasmic GPX2 staining of a subset of basal cells
Seminal vesicle
Seminal vesicle – Moderate to strong, predominantly cytoplasmic GPX2 staining of a subset of basal cells
Epididymis
Epididymis – GPX2 staining is absent in the cauda epididymis
Epididymis
Epididymis – Weak to moderate, predominantly nuclear GPX2 staining of basal cells
Testis

Female Tissues

Breast
Uterus, ectocervix
Uterus, ectocervix – Moderate nuclear and cytoplasmic GPX2 staining of basal and suprabasal cells
Uterus, ectocervix
Uterus, ectocervix – Weak nuclear and cytoplasmic GPX2 staining of basal and suprabasal cells
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion)
Uterus, myometrium
Fallopian tube, mucosa
Ovary, corpus luteum
Placenta (amnion and chorion)
Placenta, early
Placenta, mature

Muscle, connective & soft tissue

Skeletal muscle
Aorta, media
Heart muscle
Heart muscle (2)
Urinary bladder, muscular wall
Appendix, muscular wall
Colon descendens, muscular wall

Skin

Skin
Skin – Absence of GPX2 staining in this sample of epidermis
Skin
Skin – Significant nuclear and cytoplasmic GPX2 staining in the epidermis. Decreasing staining intensity from basal to apical cell layers
Skin, hairfollicel and sebaceous glands
Skin, hairfollicel and sebaceous glands – Weak to moderate nuclear and cytoplasmic GPX2 staining of peripheral germinative cells of sebaceous glands

Bone Marrow & lymphoid tissues

Bone marrow
Thymus
Spleen
Lymph node
Tonsil