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Cancer Tissues
GPX2
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Normal Tissues
Endocrine Tissues
Adrenal gland
Adrenal gland – GPX2 negative adrenocortical adenoma
Adrenal gland
Adrenal gland – GPX2 negative pheochromocytoma
Thyroid
Thyroid – GPX2 negative anaplastic carcinoma
Thyroid
Thyroid – GPX2 negative papillary carcinoma
Thyroid
Thyroid – Medullary cancer with moderate, predominantly cytoplasmic GPX2 staining of tumor cells
Respiratory system
Lung
Lung – Adenocarcinoma with strong GPX2 staining of all tumor cells
Proximal digestive tract
Oral cavity
Oral cavity – Squamous cell carcinoma with very intense, cytoplasmic and nuclear GPX2 staining of tumor cells
Esophagus
Esophagus – Adenocarcinoma with strong cytoplasmic and nuclear GPX2 staining of tumor cells
Esophagus
Esophagus – Squamous cell carcinoma with moderate to strong cytoplasmic and nuclear GPX2 staining of all tumor cells
Salivary gland
Salivary gland – Warthin tumor with strong GPX2 positivity of a fraction of epithelial tumor cells
Gastronintestinal tract
Stomach
Stomach – Gastric adenocarcinoma (diffuse type) with strong cytoplasmic and nuclear GPX2 positivity of tumor cells
Stomach
Stomach – Gastric adenocarcinoma showing a very intense GPX2 staining of all tumor cells
Stomach
Stomach – GPX2 negative gastrointestinal stromal tumor (GIST)
Colon
Colon – Colorectal adenocarcinoma showing an intense, cytoplasmic and nuclear GPX2 staining of tumor cells
Colon
Colon – Colorectal adenocarcinoma with strong, cytoplasmic and nuclear GPX2 staining of tumor cells
Liver, Gallbladder, Pancreas
Liver
Liver – Cholangiocellular carcinoma with strong GPX2 staining of _ 90_ tumor cells
Liver
Liver – Hepatocellular carcinoma with moderate GPX2 immunostaining of tumor cells
Pancreas
Pancreas – Ductal adenocarcinoma with intense GPX2 positivity of all tumor cells
Kidney, urinary bladder
Kidney
Kidney – GPX2 negative clear cell carcinoma
Kidney
Kidney – GPX2 negative papillary renal cell carcinoma
Urinary bladder
Urinary bladder – Muscle-invasive urothelial carcinoma with moderate to strong cytoplasmic and nuclear GPX2 immunostaining of _90_ of tumor cells
Male tissues
Prostate
Prostate – GPX2 negative adenocarcinoma (Gleason 3+3=6)
Testis
Testis – Seminoma with moderate to strong cytoplasmic and nuclear GPX2 immunostaining of tumor cells
Female Tissues
Breast
Breast – GPX2 negative invasive breast cancer of no special type (NST)
Breast
Breast – GPX2 negative invasive lobular breast cancer
Uterus
Uterus – Cervical adenocarcinoma exhibiting a weak to moderate, predominantly cytoplasmic GPX2 staining of tumor cells
Ovary
Ovary – Brenner tumor with strong GPX2 staining of tumor cell nests
Ovary
Ovary – GPX2 negative clear cell carcinoma
Ovary
Ovary – GPX2 negative serous high-grade carcinoma
Bone Marrow & lymphoid tissues
Lymph node
Lymph node – GPX2 negative Hodgkin’s lymphoma