Cancer Tissues

C-Peptide

Endocrine Tissues

Adrenal gland

Adrenal gland – C-peptide negative adrenocortical adenoma

Adrenal gland

Adrenal gland – C-peptide negative pheochromocytoma

Thyroid

Thyroid – C-peptide negative anaplastic carcinoma

Thyroid

Thyroid – C-peptide negative medullary carcinoma

Thyroid

Thyroid – C-peptide negative papillary carcinoma

Respiratory system

Lung

Lung – C-peptide negative adenocarcinoma

Proximal digestive tract

Esophagus

Esophagus – C-peptide negative adenocarcinoma

Esophagus

Esophagus – C-peptide negative squamous cell carcinoma

Salivary gland

Salivary gland – C-peptide negative Warthin tumor

Gastronintestinal tract

Stomach

Stomach – C-peptide negative gastric adenocarcinoma (diffuse type)

Stomach

Stomach – C-peptide negative gastrointestinal stromal tumor (GIST)

Colon

Colon – C-peptide negative colorectal adenocarcinoma

Liver, Gallbladder, Pancreas

Liver

Liver – C-peptide negative cholangiocellular carcinoma

Liver

Liver – C-peptide negative hepatocellular carcinoma

Pancreas

Pancreas – C-peptide negative acinar cell carcinoma

Pancreas

Pancreas – C-peptide negative neuroendocrine tumor. (2)

Pancreas

Pancreas – C-peptide negative neuroendocrine tumor

Pancreas

Pancreas – Neuroendocrine tumor (Insulinoma) with strong C-peptide immunostaining of tumor cells

Pancreas

Pancreas – Neuroendocrine tumor (insulinoma) with strong C-peptide positivity of tumor cells

Pancreas

Pancreas – Neuroendocrine tumor (insulinoma) with strong C-peptide staining of all tumor cells

Pancreas

Pancreas – Neuroendocrine tumor with many intermingled C-peptide positive cells

Pancreas

Pancreas – Neuroendocrine tumor with numerous intermingled cells showing strong C-peptide staining

Kidney, urinary bladder

Kidney

Kidney – C-peptide negative chromophobe renal cell carcinoma

Kidney

Kidney – C-peptide negative clear cell carcinoma

Kidney

Kidney – C-peptide negative papillary renal cell carcinoma

Urinary bladder

Urinary bladder – C-peptide negative muscle-invasive urothelial carcinoma

Male tissues

Prostate

Prostate – C-peptide negative adenocarcinoma (Gleason 3+3=6)

Testis

Testis – C-peptide negative embryonal carcinoma

Testis

Testis – C-peptide negative seminoma

Female Tissues

Breast

Breast – C-peptide negative invasive breast cancer of no special type (NST)

Breast

Breast – C-peptide negative invasive lobular breast cancer

Ovary

Ovary – C-peptide negative serous high-grade carcinoma

Muscle, connective & soft tissue

Penis

Penis – C-peptide negative squamous cell carcinoma

Bone Marrow & lymphoid tissues

Lymph node

Lymph node – C-peptide negative diffuse large B-cell lymphoma