Normal Tissues

Brain

Cerebrum, grey matter
Cerebrum, grey matter – Distinct nuclear TIGIT staining of a subset of glial cells
Cerebrum, white matter
Cerebrum, white matter – Distinct nuclear TIGIT staining of a subset of glial cells
Cerebrum, white matter
Cerebrum, white matter – Distinct nuclear TIGIT staining of a subset of glial cells (2)
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer, white matter)
Cerebellum (white matter)

Endocrine Tissues

Adrenal gland
Thyroid gland
Parathyroid gland
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe

Respiratory system

Lung

Proximal digestive tract

Tonsil, surface epithelium
Tonsil, surface epithelium – Distinct TIGIT staining of few lymphocytes
Parotid gland

Gastronintestinal tract

Stomach, antrum (2)
Stomach, antrum
Stomach, corpus
Duodenum, Brunner gland
Colon descendens, mucosa

Liver, Gallbladder, Pancreas

Liver
Pancreas

Kidney, urinary bladder

Kidney, cortex
Kidney, medulla
Urinary bladder, urothelium

Male tissues

Prostate
Seminal vesicle
Epididymis
Testis

Female Tissues

Breast
Uterus, ectocervix
Uterus, endocervix
Uterus, endometrium (proliferation)
Uterus, endometrium (pregnancy) (2)
Uterus, endometrium (pregnancy)
Uterus, endometrium (secretion)
Uterus, myometrium
Fallopian tube, mucosa
Ovary, stroma
Ovary, corpus luteum
Placenta (amnion and chorion)
Placenta, early
Placenta, mature

Muscle, connective & soft tissue

Skeletal muscle
Aorta, media
Heart muscle
Urinary bladder, muscular wall
Appendix, muscular wall
Colon descendens, muscular wall

Skin

Skin
Skin, hairfollicel and sebaceous glands
Anal canal, skin

Bone Marrow & lymphoid tissues

Bone marrow
Thymus
Thymus – Rather weak TIGIT staining of some lymphocytes
Spleen
Spleen – Distinct TIGIT staining of few lymphocytes.(2)
Spleen
Spleen – Distinct TIGIT staining of few lymphocytes
Lymph node
Lymph node – Most TIGIT positive lymphocytes are in the interfollicular area while the strongest TIGIT staining occurs in the few labeled lymphocytes in a small germinal centre
Tonsil
Tonsil – Distinct TIGIT staining of subsets of follicular and interfollicular lymphocytes
Tonsil
Tonsil – Most TIGIT positive lymphocytes are in the interfollicular area while the strongest TIGIT staining occurs in a subset of lymphocytes in the germinal centre
Tonsil