Cancer Tissues

Tyrosine Hydroxylase / TH

Endocrine Tissues

Adrenal gland

Adrenal gland – Pheochromocytoma with intense TH positivity of tumor cells

Adrenal gland

Adrenal gland – Pheochromocytoma with strong TH immunostaining of all tumor cells

Adrenal gland

Adrenal gland – Pheochromocytoma with strong TH staining of all tumor cells

Adrenal gland

Adrenal gland – Pheochromocytoma with variable, mostly intense TH staining of tumor cells

Adrenal gland

Adrenal gland – Pheochromocytoma with weak to moderate TH staining of a small fraction of tumor cells

Adrenal gland

Adrenal gland – TH negative adrenocortical adenoma

Thyroid

Thyroid – TH negative medullary carcinoma

Thyroid

Thyroid – TH negative papillary carcinoma

Medullary carcinoma of the thyroid containing a small number of dispersed cells with strong TH positivity

Proximal digestive tract

Esophagus

Esophagus – TH negative adenocarcinoma

Salivary gland

Salivary gland – TH negative Warthin tumor

Gastronintestinal tract

Stomach

Stomach – TH negative gastric adenocarcinoma (diffuse type)

Stomach

Stomach – TH negative gastric adenocarcinoma

Stomach

Stomach – TH negative gastrointestinal stromal tumor (GIST)

Colon

Colon – TH negative colorectal adenocarcinoma

Liver, Gallbladder, Pancreas

Liver

Liver – TH negative cholangiocellular carcinoma

Liver

Liver – TH negative hepatocellular carcinoma

Pancreas

Pancreas – TH negative ductal adenocarcinoma

Pancreas

Pancreas – TH negative neuroendocrine tumor

Kidney, urinary bladder

Kidney

Kidney – TH negative clear cell carcinoma

Kidney

Kidney – TH negative papillary renal cell carcinoma

Urinary bladder

Urinary bladder – TH negative muscle-invasive urothelial carcinoma

Male tissues

Prostate

Prostate – TH negative adenocarcinoma (Gleason 3+3=6)

Testis

Testis – TH negative seminoma

Female Tissues

Breast

Breast – TH negative invasive breast cancer of no special type (NST)

Breast

Breast – TH negative invasive lobular breast cancer

Skin

Anal canal

Anal canal – TH negative squamous cell carcinoma